Summary and impact
Summary
The LICOMAR project addresses the critical challenge of bone tissue repair by developing innovative, sustainable coatings for prosthetic and implantable elements (PIE). This project focuses on enhancing osseointegration and reducing inflammatory responses to improve the long-term success of PIE. The LICOMAR team utilizes natural hydroxyapatite (NHA) derived from fish bones as an alternative to synthetic HA, supporting circular economy principles by reusing fish industry waste. The NHA is complemented by green-synthesized silver nanoparticles (Ag NPs) functionalized with/from Porphyridium purpureum extracts, which offer anti-inflammatory properties essential for PIE applications. LICOMAR employs Matrix-Assisted Pulsed Laser Evaporation (MAPLE) to achieve precise, uniform coatings. The MAPLE method is particularly suited for depositing delicate functionalised Ag NPs and NHA onto PIE-like surfaces. By merging advanced laser deposition technology with sustainable material sourcing, LICOMAR aims to produce high-performance, cost-effective coatings that enhance implant integration and resilience. This approach not only improves clinical outcomes in bone repair but also advances eco-friendly practices in biomedical material development.
Socio-economic impact
The LICOMAR project contributes to improving bone tissue repair by developing advanced coatings that enhance osseointegration and reduce inflammatory responses in prosthetic and implantable elements. This can increase implant longevity, reduce revision surgeries, and lower healthcare costs while improving patient quality of life. The use of NHA derived from fish bone waste supports circular economy principles and promotes sustainable resource use. Additionally, the project encourages innovation in eco-friendly biomedical materials and strengthens collaboration between research, healthcare, and industry sectors.
Cognitive impact
LICOMAR advances scientific knowledge in biomaterials, nanotechnology, and laser-based deposition techniques. By combining NHA, green-synthesized Ag NPs, and MAPLE deposition, the project explores new strategies for multifunctional implant coatings. The research will improve understanding of implant–tissue interactions and contribute to the development of sustainable, high-performance biomaterials for biomedical applications. The project is also expected to generate new scientific publications and foster interdisciplinary research collaborations.